Adrenal cancer is the most common cause of death from tumors in the United States. As with any cancer, early detection is key to a better outcome. But because adrenal cancers don’t typically present with obvious symptoms, it can be hard for patients to know when they should see their doctor about their symptoms or get tested for this disease. This article will discuss some signs and symptoms of adrenal cancers and tumors.

Signs and Symptoms of Adrenal Cancers and Adrenal Tumors

Signs and symptoms of adrenal cancer include

  • Unusual fatigue. Fatigue is one of the most common signs of adrenal cancer, and it can be difficult to distinguish from other causes of tiredness.
  • Irregular menstrual periods. Irregular menstrual periods, including missed periods or heavy bleeding during menstruation, indicate that something may be wrong with your body’s hormone levels if they persist for over a few months.
  • Increased and night sweating: Excessive sweating can also occur when you sleep at night due to an overactive sympathetic nervous system (the part that controls our “fight-or-flight” response). This will cause your body temperature to rise above normal levels. At the same time, you sleep due to increased nervousness in addition to high blood pressure caused by stress hormones such as cortisol and norepinephrine being released into circulation throughout your system all day long instead of just during stressful situations like work deadlines at work meetings, etc., which means there’s no way around getting enough sleep every single night if possible because the lack thereof may lead directly back towards developing these kinds cancers later down the line especially if left untreated early enough before any serious damage occurs within organs such as liver pancreas lungs, etc., so try not to spend too much time worrying about other things besides yourself first before worrying about others.

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Symptoms of adrenal tumors include

The signs and symptoms of adrenal tumors include:

  • the increased appetite (hunger)
  • weight gain
  • increased thirst
  • increased urination
  • nausea, vomiting, or diarrhea (other conditions can also cause these symptoms). The most common symptom is fatigue. Other common symptoms include weakness, depression, anxiety, and muscle weakness in the legs.

Adrenal cancers and tumors can cause many different signs and symptoms.

The adrenal glands are found beyond the kidneys. They produce hormones that regulate metabolism, blood pressure, and electrolyte balance. Adrenal cancers and tumors can cause many different signs and symptoms depending on their size, location within the gland, type of cancer cells involved in their growth, and whether they have spread to other areas in your body (metastasized).

In addition to these general signs and symptoms associated with adrenal cancer or tumors:

Unusual Fatigue

Fatigue is a common symptom of adrenal cancer, and many other conditions can also cause it. If you have unusual fatigue that lasts more than one month, talk to your doctor about whether it could be related to your adrenal glands.

  • Unusual Fatigue – If you’re tired all the time or feel weak and drained even after getting enough sleep, this could be a sign of adrenal cancer or tumors. Anemia may also be present if the disease is advanced and has spread (metastasized) in your body.
  • Weight Gain – Some people experience weight gain with this type of cancer because their bodies require more calories as they become weaker from a lack of energy production by their adrenal glands.*

Irregular Menstrual Periods

Irregular menstrual periods are defined as a cycle that is either shorter or longer than usual or occurs at intervals of more than 35 days apart.

Irregular periods can be caused by many factors, including:

  • Hormonal imbalances (such as those related to polycystic ovarian syndrome).
  • Medications such as steroids and birth control pills.
  • Stressful life events such as a death in the family or divorce.

Increased Sweating and Night Sweating

Night sweats are a sign of many things, including anxiety and stress. However, if you have increased sweating during the day and night sweats that don’t seem to go away with treatment, it may be a sign of an adrenal tumor or cancer.

Headache and Migraine Symptoms

Signs and Symptoms of Adrenal Cancers and Adrenal Tumors

You may experience headache or migraine symptoms if you have an underlying medical condition that causes headaches, such as high blood pressure or diabetes.

Medications can also cause headaches and migraines including antihistamines; antidepressants; antihypertensives (high blood pressure medicines) such as beta blockers, calcium channel blockers and ACE inhibitors; antidepressants including tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs) and serotonin norepinephrine reuptake inhibitors (SNRIs); antipsychotic medications used to treat schizophrenia or bipolar disorder; medications used to treat anxiety disorders like benzodiazepines/benzodiazepine analogues such as Xanax®, Ativan®, Klonopin® etc.; narcotics used for pain management like hydrocodone/acetaminophen combinations like Vicodin™ or oxycodone/acetaminophen combinations like Percocet™ which can cause nausea & vomiting along with constipation leading to dehydration which causes headaches when combined with dehydration caused by sweating due to hot weather conditions during summer months that leads many people outside where they sweat more than usual.”

Water Retention and Bloating

Water retention and bloating are common symptoms of adrenal cancers and tumors. Water retention can be caused by an overproduction of aldosterone, a hormone your adrenal glands produce that helps regulate blood pressure, sodium levels, and potassium excretion.

Bloating may also occur due to low cortisol levels that cause salt and water retention. This condition could result in swelling around your ankles and puffiness under your eyes due to fluid accumulation there too! The good news is there are measures you can take at home (and with medical help) before resorting to surgery or other invasive procedures like draining the fluid out through a needle inserted into an area called “peripheral plexus.”

High Blood Pressure (Hypertension) or Low Blood Pressure (Hypotension)

High blood pressure (hypertension) is a common sign of an adrenal tumor. Hypertension is defined as having a systolic blood pressure greater than 140 mm Hg or diastolic blood pressure greater than 90 mm Hg. The most common signs of high blood pressure include headaches, dizziness, and chest pain.

Low blood pressure can also be a symptom of adrenal cancer or tumor. Low blood pressure (hypotension) occurs when the heart does not pump enough oxygenated blood to meet the needs of tissues throughout your body; this results in fatigue, nausea, and fainting spells if left untreated for too long. Low blood pressure may also indicate heart failure if it persists without treatment, such as surgery or medication.

Abdominal Pain and Intermittent Pain in the Back, Chest, or Arm or Leg

Abdominal pain and intermittent pain in the back, chest, arm, or leg

Pain can be sharp or dull. The intensity of the pain may increase with physical exertion. It may also be constant or intermittent on one or both sides of the body.

Make sure you see a doctor if you notice any of these symptoms.

You should see a doctor if you notice any of these symptoms.

  • Don’t wait to see if they go away on their own.
  • Don’t try to self-diagnose or self-medicate for an adrenal cancer or tumor–it may be too late by the time you get diagnosed with adrenal cancer, which can be fatal if left untreated.
  • Ignore the problem at your own risk: ignoring an undiagnosed problem could lead to life-threatening complications later on down the road when treatment is more difficult because it’s progressed further than it would have otherwise been able to do so before being caught in time by a doctor’s intervention (or even just noticing). Suppose there’s something wrong with one part of your body and its function. In that case, it stands to reason that there might be other parts/systems/functions that have also been affected by whatever caused this initial change–and ignoring those secondary changes could make things worse overall!


If you have any of these symptoms, you must see a doctor. Don’t wait until the symptoms get worse or more frequent. The sooner you start treatment, the better your chances for survival and recovery from adrenal cancer or tumor disease.

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